Research Article
Development and Validation of a Stability-Indicating HPTLC Method for Analysis of Rasagiline Mesylate in the Bulk Drug and Tablet Dosage Form
Table 6
Degradation of rasagiline mesylate.
| | Condition | Time (h) | Recovery (%) | (%) value of degraded products |
| | 5 M HCl refluxed at 80°C | 5 | 47.50 | 7.53, 44.96 | | 5 M NaOH refluxed at 80°C | 3 | 46.92 | 22.92, 11.96, 18.75 | | H2O2 30% v/v refluxed at 80°C | 4 | 63.30 | 5.45, 9.89, 21.37 | | Daylight | 24 | 100 | None detected | | Dry heat degradation | 10 | 100 | None detected | | Neutral hydrolysis (Reflux at 50º C) | 12 | 100 | None detected |
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