Chromatography Research International

Research Article

Development and Validation of Dissolution Test for Fluconazole Capsules by HPLC and Derivative UV Spectrophotometry

Table 2

Recovery data for fluconazole standard solutions added to the placebo by using the proposed HPLC and UV-FDS.
MethodAdded amount (μg/mL)Founda amount (μg/mL)Bias (%)Recoverya (%) R.S.D.
HPLC135133.920.80
150148.001.33
165161.282.25
180177.301.50
195192.411.33
FDS135134.540.34
150147.511.66
165161.931.86
180175.682.40
195190.962.07
aAverage of three replicates.