Neopterin as a Marker of Response to Antiviral Therapy in Hepatitis C Virus Patients

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td align="left"></td><td align="left">All patients</td><td align="center">Responders</td><td align="center">Nonresponders</td><td align="center"><svg height="11.175" id="M6" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.9375 11.175" width="10.9375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,0,0,-.017,.062,11.113)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
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</svg> value</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td align="left">Neopterin (nmol/L)</td><td align="center"><span style="width: 58.887501px;"><svg height="11.375" id="M7" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.887501 11.375" width="58.887501" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,0,0,-.017,.062,11.113)"><path d="M857 650l-6 -28q-44 -4 -61.5 -16.5t-29.5 -48.5q-11 -32 -37 -166l-78 -399h-29l-351 537h-4l-56 -276q-24 -120 -24 -164q0 -35 17.5 -46t75.5 -15l-6 -28h-245l7 28q41 2 62 14t31 44q10 30 41 171l53 245q8 44 6.5 60.5t-14.5 33.5q-10 15 -27 19.5t-64 6.5l6 28h153
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</svg></span></td><td align="center"><span style="width: 58.887501px;"><svg height="11.375" id="M9" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.887501 11.375" width="58.887501" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,0,0,-.017,.062,11.113)"><path d="M857 650l-6 -28q-44 -4 -61.5 -16.5t-29.5 -48.5q-11 -32 -37 -166l-78 -399h-29l-351 537h-4l-56 -276q-24 -120 -24 -164q0 -35 17.5 -46t75.5 -15l-6 -28h-245l7 28q41 2 62 14t31 44q10 30 41 171l53 245q8 44 6.5 60.5t-14.5 33.5q-10 15 -27 19.5t-64 6.5l6 28h153
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</svg></span></td><td align="left"> </td></tr><tr><td align="left">Mean ± standard deviation</td><td align="center"><span style="width: 74.362503px;"><svg height="11.4" id="M10" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 74.362503 11.4" width="74.362503" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td><td align="center"><span style="width: 74.362503px;"><svg height="11.2875" id="M11" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 74.362503 11.2875" width="74.362503" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td><td align="center"><span style="width: 74.362503px;"><svg height="11.2875" id="M12" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 74.362503 11.2875" width="74.362503" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td><td align="center">0.015 (Student's <svg height="10.3875" id="M13" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 5.9250002 10.3875" width="5.9250002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,0,0,-.017,.062,10.125)"><path d="M324 430l-26 -36l-112 -4l-55 -265q-13 -66 7 -66q13 0 44.5 20t50.5 40l17 -24q-38 -40 -85.5 -73.5t-87.5 -33.5q-50 0 -21 138l55 262h-80l-2 8l25 34h66l25 99l78 63l10 -9l-37 -153h128z" id="x1D461"></path></g>
</svg>-test)</td></tr><tr><td align="left">Median [25th–75th percentile]</td><td align="center">19.4 [12.2–36.4]</td><td align="center">13.0 [9.4–25.7]</td><td align="center">24.4 [15.0–26.8]</td><td align="center">&lt;.0001 (Wilcoxon rank-sum test)</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Neopterin concentrations in HCV responders and nonresponders to antiviral therapy.

Hepatitis Research and Treatment

tab1

Table 1

Table 1: Neopterin as a Marker of Response to Antiviral Therapy in Hepatitis C Virus Patients 