Research Article

Chromatin-Associated Proteins Revealed by SILAC-Proteomic Analysis Exhibit a High Likelihood of Requirement for Growth Fitness under DNA Damage Stress

Figure 4

Top ranked proteins by SILAC ratios are enriched for nucleus-localized proteins and CHRAP-associated functions. (a) Nucleus-localized proteins are enriched in the top 10% ranked proteins by SILAC. Display is identical to Figure 3(d). Levels of nucleus-localized (nuc), dual-localized (nuc; cyt), and cytoplasm-localized (cyt) proteins are shown. (b) Top 10% ranked proteins by SILAC are enriched for CHRAP-associated functions based on gene ontology analysis.
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