The HOAP protein family. The HOAP proteins were identified by tBLASTn search in Flybase (http://flybase.org/blast/) and are represented as rectangles. For the unannotated new sequenced genomes, BLAST analysis using 5 kbp upstream and downstream the cav and cav-dupl genes allowed to identify the orthologous region in the melanogaster genome. A same color code and a line connecting proteins indicate that the synteny block is conserved between the corresponding genes.