Review Article
Update on Peptic Ulcers in the Pediatric Age
| | Author/yr/country | Study methods | Number of children examined | PUD | PUB | HP infection | NSAID use |
| | Kalach et al. [15] 2010; Europe | Multicenter, prospective | 694 | 56/694 (8%) | n.d.a. | 15/56 (27%) | 8/56 (14%) |
| | Brown et al. [16] 2012; US | Multicenter
(on national registries), retrospective | 29.3 million | 7280 | 1267 (17.4% of PUD) | n.d.a. | n.d.a. |
| | Shu-Ching et al. [14] 2009; Taiwan | Monocenter, retrospective, and prospective | 1234 | 67 (5.4%)
gastric 27 (40.3%) duodenal 40 (59.7%) | 43 (64.2% of PUD) | 32 (47.7%) | 11 (16.5%) |
| | Egbaria et al. [17] 2008; Israel | Monocenter, retrospective | 751 | 169 (22.5%)
(i) ulcers 51 (6.8%), erosions 118 (15.7%);
(ii) gastric 124 (73.3%), duodenal 58 (34.3%) | 4 (2.4% of PUD) | 112 (66.3%) | 34 (20.1%) |
| | El Mouzan and abdullah [18] 2004; Saudi Arabia | Monocenter, retrospective, and prospective | 521 | 24 (5%)
gastric 4 (17%), duodenal 20 (92%) | 5 (21% of PUD) | 13/15 (87%) | nda |
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yr: year; PUD: peptic ulcer disease; PUB: peptic ulcer bleeding; HP: Helicobacter pylori; NSAID: nonsteroidal anti-inflammatory drugs; n.d.a.: no data available.
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