Biochemical and Pharmacological Characterization of TLBbar, a New Serine Protease with Coagulant Activity from Bothrops barnetti Snake Venom
Figure 3
Sequence alignment of TLBbar with other SVSPs with thrombin-like activity. Calobin of Agkistrodon caliginosus GI: 1389589 [34]; Crotalase (Cro) of Crotalus adamanteus GI: 384951520 [35]; Flavoxobin (Fla) of Trimeresurus flavoviridis GI: 3915685 [36]; Bilineobin (Bil) of Agkistrodon bilineatus GI: 998903 [50]; Gyroxin (Gyr) of Lachesis muta muta GI: 998903 [51]; Ancrod (Anc) of Calloselasma rhodostoma GI: 247212 [52]; Batroxobin (Bat) of Bothrops atrox GI: 114837 [37], and Bot TL (Bot) of Bothrops jararaca GI: 999161 [53]. The cysteine and histidine residues (*) are highly conserved in all sequences.
