Research Article
A Fibrin-Based Tissue-Engineered Renal Proximal Tubule for Bioartificial Kidney Devices: Development, Characterization and In Vitro Transport Study
Table 1
Transport characteristics of single fiber proximal renal tubules.
| | | Absolute | Fractional | FITC-inulin | FITC-inulin | Flux | | readsorption | readsorption | recovery | concentration | (LMH) | | rate (μL/hr) | rate (μL/hr) | (%) | ratio (/) |
| | Cell free | 200.1 ± 59.1 | 9.0 ± 2.3 | 88.6 ± 4.7 | 0.97 ± 0.05 | 30.3 ± 9.0 | | (baseline) |
| | Baseline | 12.2 ± 13.7 | 0.5 ± 0.6 | 104.0 ± 6.6 | 1.05 ± 0.06 | 1.8 ± 2.1 | | Albumin | 25.9 ± 18.5 | 1.7 ± 1.5 | 104.0 ± 9.8 | 1.07 ± 0.11 | 3.9 ± 2.8 | | Ouabain | 18.7 ± 16.7 | 0.7 ± 0.7 | 101.9 ± 6.5 | 1.03 ± 0.07 | 2.8 ± 2.5 |
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Results are biologically replicated and expressed as mean ± standard deviation; .
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