Research Article

Validated Stability Indicating RP-HPLC Method for Simultaneous Estimation of Codeine Phosphate and Chlorpheniramine Maleate from Their Combined Liquid Dosage Form

Table 7

Robustness studies.

Sl. noParameterModificationRetention time (min)

1Flow rate0.8 mL/min3.2, 9.13
1.2 mL/min3.31, 9.32
2pH2.83.63, 9.7
3.23.3, 8.9