Development and Validation of an RP-HPLC Method for Estimation of Chlorpheniramine Maleate, Ibuprofen, and Phenylephrine Hydrochloride in Combined Pharmaceutical Dosage Form

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left">Parameter</td><td align="center">CPM</td><td align="center">IBU</td><td align="center">PHE</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left">Retention time (min)</td><td align="center">4.2</td><td align="center">13.6</td><td align="center">2.7</td></tr><tr><td align="left">Theoretical plates  </td><td align="center">4155.36</td><td align="center">4324.06</td><td align="center">3986.31</td></tr><tr><td align="left">Tailing factor</td><td align="center">0.67</td><td align="center">1.03</td><td align="center">1.25</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Chromatography Research International

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Table 3

Table 3: Development and Validation of an RP-HPLC Method for Estimation of Chlorpheniramine Maleate, Ibuprofen, and Phenylephrine Hydrochloride in Combined Pharmaceutical Dosage Form 

Table 3 | Development and Validation of an RP-HPLC Method for Estimation of Chlorpheniramine Maleate, Ibuprofen, and Phenylephrine Hydrochloride in Combined Pharmaceutical Dosage Form 