Epilepsy Research and Treatment

Research Article

A Clinical-EEG Study of Sleepiness and Psychological Symptoms in Pharmacoresistant Epilepsy Patients Treated with Lacosamide

Table 1

Demography.


Patients	Age	Age at onset (yr)	Epileptic syndrome	Seizure type	AEDs before-LCM

No. 1	45	11	Symptomatic temporal lobe epilepsy (posttraumatic)	Focal limbic seizures, SG	OXC 900 mg/die; LEV 3 g/die; VPA 1,5 g/die; LTG 200 mg/die; TPM 600 mg/die; VNS
No. 2	34	13	Symptomatic temporal lobe epilepsy (postradiotherapy calcification)	Focal limbic seizures, SG	OXC 1200 mg/die; LTG 300 mg/die; LEV 3 g/die; VNS
No. 3	34	18	Probably symptomatic temporal lobe epilepsy	Focal limbic seizures, rarely SG	LEV 3,5 g/die; ZNS 200 mg/die; TPM 600 mg/die; CBZ 1600 mg/die
No. 4	76	16	Probably symptomatic frontal lobe epilepsy	Focal seizures	CBZ CR 1200 mg/die; PB 50 mg/die; LTG 200 mg/die; ZNS 450 mg/die
No. 5	43	13	Probably symptomatic temporal lobe epilepsy	Focal limbic seizures	OXC 1800 mg/die; LEV 3 g/die
No. 6	59	6	Probably symptomatic temporal lobe epilepsy	Focal limbic seizures	ZNS 100 mg/die; LEV 1 g 3/die; OXC 600 mg 3/die
No. 7	55	10	Symptomatic temporal lobe epilepsy (left HS)	Focal limbic seizures	LEV 2 g/die; OXC 2100 mg/die; TPM 300 mg/die
No. 8	51	25	Symptomatic temporooccipital epilepsy (right retrotrigonal lesion)	Focal limbic seizures	LEV 1 g 3/die; CBZ ; ZNS 200 mg/die
No. 9	26	1	Symptomatic frontal lobe epilepsy (calcifications of falx cerebri)	Nocturnal frontal seizures	CBZ 1200 mg/die; TPM 450 mg/die
No. 10	59	27	Probably symptomatic temporal lobe epilepsy	Focal limbic seizures	TPM 350 mg/die

HS: hippocampal sclerosis; SG: secondarily generalized; CBZ: carbamazepine; LEV: levetiracetam; LTG: lamotrigine; OXC: oxcarbazepine; TPM: topiramate; VNS: vagus nerve stimulation; VPA: valproic acid; ZNS: zonisamide.