Schematic picture of the cooperation network and interplays of the vegetative growth signaling pathway with the asexual and sexual development signal transduction pathways. Connections to the velvet complex, especially to VeA, are also presented. AflR, the regulatory transcription factor of toxic sterigmatocystin/aflatoxin biosynthesis, is also connected to vegetative growth signaling through PkaA. ESF: extracellular sporulation factor; P: phosphorous.