Article of the Year 2021: Medicine

Recognizing and reward the year's most outstanding articles in medicine.


Canadian Respiratory Journal
A Follow-Up Study of Lung Function and Chest Computed Tomography at 6 Months after Discharge in Patients with Coronavirus Disease 2019
Qian Wu, Lingshan Zhong, Hongwei Li, Jing Guo, Yajie Li, Xinwei Hou, Fangfei Yang, Yi Xie, Li Li, and Zhiheng Xing

Cardiology Research and Practice
Cardiac Injury Biomarkers and the Risk of Death in Patients with COVID-19: A Systematic Review and Meta-Analysis
Sami H. Alzahrani and Mohammed W. Al-Rabia

Computational and Mathematical Methods in Medicine
COVID-19 in Iran: Forecasting Pandemic Using Deep Learning
Rahele Kafieh, Roya Arian, Narges Saeedizadeh, Zahra Amini, Nasim Dadashi Serej, Shervin Minaee, Sunil Kumar Yadav, Atefeh Vaezi, Nima Rezaei, and Shaghayegh Haghjooy Javanmard

Disease Markers
Characteristics of Three Different Chemiluminescence Assays for Testing for SARS-CoV-2 Antibodies
Myriam C. Weber, Martin Risch, Sarah L. Thiel et al.

Mediators of Inflammation
COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation​​​
Mohamed M. Aboudounya and Richard J. Heads

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Internal medicine

International Journal of Hypertension
Trends in the Prevalence, Awareness, Treatment, and Control of Hypertension in Nepal between 2000 and 2025: A Systematic Review and Meta-Analysis
Raja Ram Dhungana, Achyut Raj Pandey, and Nipun Shrestha

International Journal of Nephrology
Impact of National Economy and Policies on End-Stage Kidney Care in South Asia and Southeast Asia
Suceena Alexander, Sanjiv Jasuja, Maurizio Gallieni et al.

International Journal of Pediatrics
Germinal Matrix-Intraventricular Hemorrhage: A Tale of Preterm Infants
Walufu Ivan Egesa, Simon Odoch, Richard Justin Odong et al.

Journal of Diabetes Research
The Relationship between Erythrocytes and Diabetes Mellitus
Yaqi Wang, Peiyuan Yang, Zhaoli Yan, Zhi Liu, Qiang Ma, Zehong Zhang, Yunxia Wang, and Yan Su

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Behavioural Neurology
Revisiting Apathy in Alzheimer’s Disease: From Conceptualization to Therapeutic Approaches​​
Antonio L. Teixeira, Mitzi M. Gonzales, Leonardo Cruz de Souza, and Sara L. Weisenbach

Biochemistry Research International​​​
Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer’s Disease Mutations
Alejandro Soto-Ospina, Pedronel Araque Marín, Gabriel de Jesús Bedoya, and Andrés Villegas Lanau

Neural Plasticity
Role of BDNF-mTORC1 Signaling Pathway in Female Depression
Xianquan An, Xiaoxiao Yao, Bingjin Li, Wei Yang, Ranji Cui, Guoqing Zhao, and Yang Jin

Parkinson’s Disease
Staging Parkinson’s Disease Combining Motor and Nonmotor Symptoms Correlates with Disability and Quality of Life
D. Santos García, T. De Deus Fonticoba, J. M. Paz González et al.


Brain image

Pain management

Occupational Therapy International
Leisure and Productivity in Older Adults with Cancer: A Systematic Review
Cynthia Engels, Robin Bairet, Florence Canoui-Poitrine, and Marie Laurent

Pain Research and Management
Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations
Yaping Chang, Meng Zhu, Christopher Vannabouathong, Raman Mundi, Roland S. Chou, and Mohit Bhandari

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Want to read more winning articles?

We're not just recognizing impactful articles in medicine.

Follow the link below to discover the winners of this year's Article of the Year Award across the entire Hindawi portfolio.  

Article of the Year 2021
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Article of the Year Award: Outstanding research contributions of 2021, as selected by our Chief Editors. Read the winning articles.