Table of Contents Author Guidelines Submit a Manuscript
Abstract and Applied Analysis
Volume 2014, Article ID 173952, 5 pages
http://dx.doi.org/10.1155/2014/173952
Research Article

Antimicrobial Resistance within Host: A Population Dynamics View

1Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
2Chongqing Research Center for Information and Automation Technology, Chongqing Academy of Science & Technology, Chongqing 401123, China

Received 27 December 2013; Accepted 19 January 2014; Published 23 February 2014

Academic Editor: Weiming Wang

Copyright © 2014 Chunji Huang and Aijun Fan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. Godlee, “Antimicrobial resistance-an unfolding catastrophe,” British Medical Journal, vol. 346, article f1663, 2013. View at Publisher · View at Google Scholar
  2. D. Dubnau and R. Losick, “Bistability in bacteria,” Molecular Microbiology, vol. 61, no. 3, pp. 564–572, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Eldar and M. B. Elowitz, “Functional roles for noise in genetic circuits,” Nature, vol. 467, no. 7312, pp. 167–173, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. M. E. Lidstrom and M. C. Konopka, “The role of physiological heterogeneity in microbial population behavior,” Nature Chemical Biology, vol. 6, no. 10, pp. 705–712, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Maisonneuve, M. Castro-Camargo, and K. Gerdes, “(p)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity,” Cell, vol. 154, no. 5, pp. 1140–1150, 2013. View at Publisher · View at Google Scholar
  6. F. E. Berkowitz, “Antibiotic resistance in bacteria,” Southern Medical Journal, vol. 88, no. 8, pp. 797–804, 1995. View at Publisher · View at Google Scholar · View at Scopus
  7. F. C. Tenover and J. M. Hughes, “The challenges of emerging infectious diseases: development and spread of multiply-resistant bacterial pathogens,” Journal of the American Medical Association, vol. 275, no. 4, pp. 300–304, 1996. View at Publisher · View at Google Scholar · View at Scopus
  8. A. M. Garber, “Antibiotic exposure and resistance in mixed bacterial populations,” Theoretical Population Biology, vol. 32, no. 3, pp. 326–346, 1987. View at Publisher · View at Google Scholar · View at Zentralblatt MATH · View at Scopus
  9. A. S. Kessel and M. Sharland, “The new UK antimicrobial resistance strategy and action plan,” British Medical Journal, vol. 346, article f1601, 2013. View at Publisher · View at Google Scholar
  10. M. Lipsitch, C. T. Bergstrom, and B. R. Levin, “The epidemiology of antibiotic resistance in hospitals: paradoxes and prescriptions,” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 4, pp. 1938–1943, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. M. J. M. Bonten, D. J. Austin, and M. Lipsitch, “Understanding the spread of antibiotic resistant pathogens in hospitals: mathematical models as tools for control,” Clinical Infectious Diseases, vol. 33, no. 10, pp. 1739–1746, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. N. Jumbe, A. Louie, R. Leary et al., “Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy,” Journal of Clinical Investigation, vol. 112, no. 2, pp. 275–285, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Sotto and J. P. Lavigne, “A mathematical model to guide antibiotic treatment strategies,” BMC Medicine, vol. 10, article 90, 2012. View at Publisher · View at Google Scholar
  14. P. Ankomah and B. R. Levin, “Two-drug antimicrobial chemotherapy: a mathematical model and experiments with Mycobacterium marinum,” PLoS Pathogens, vol. 8, no. 1, Article ID e1002487, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. I. H. Spicknall, B. Foxman, C. F. Marrs, and J. N. S. Eisenberg, “A modeling framework for the evolution and spread of antibiotic resistance: literature review and model categorization,” American Journal of Epidemiology, vol. 178, no. 4, pp. 508–520, 2013. View at Publisher · View at Google Scholar
  16. C. C. McCluskey and J. S. Muldowney, “Bendixson-Dulac criteria for difference equations,” Journal of Dynamics and Differential Equations, vol. 10, no. 4, pp. 567–575, 1998. View at Publisher · View at Google Scholar · View at Zentralblatt MATH · View at Scopus
  17. O. Osuna and G. Villasenor, “On the Dulac functions,” Qualitative Theory of Dynamical Systems, vol. 10, no. 1, pp. 43–49, 2011. View at Publisher · View at Google Scholar · View at Zentralblatt MATH
  18. K. Lewis, “Persister cells, dormancy and infectious disease,” Nature Reviews Microbiology, vol. 5, no. 1, pp. 48–56, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. M. D. LaFleur, Q. Qi, and K. Lewis, “Patients with long-term oral carriage harbor high-persister mutants of Candida albicans,” Antimicrobial Agents and Chemotherapy, vol. 54, no. 1, pp. 39–44, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. K. R. Allison, M. P. Brynildsen, and J. J. Collins, “Metabolite-enabled eradication of bacterial persisters by aminoglycosides,” Nature, vol. 473, no. 7346, pp. 216–220, 2011. View at Publisher · View at Google Scholar · View at Scopus