Hopf Bifurcation and Stability of Periodic Solutions for Delay Differential Model of HIV Infection of CD4⁺ T-cells

Table 1

Parameter definitions and estimations used in the underlying model.

Parameter	Notes	Estimated Value	Range	Source
	Source of uninfected CD4^+ T-cells	10	0–10	[26]
	Rate of infection	0.1	0.00001–0.5	[26]
	Total carrying capacity	1500	1500	[26]
	Logistic growth term	0.03	0.03–3	[26]
	Mortality rate of CD4^+ T-cells	0.06	0.007–0.1	[26]
	Antiretroviral (RTI) therapy	0.9	0-1	see text
	Infected cells died out naturally	0.3	0.2–1.4	[26]
	Apoptosis rate of infected cells	0.2	0.2	[26]
	Clearance rate of infected cells	1	0.001–1	[26]
	Protease inhibitor therapy	0.9	0, 1	see text
	Rate of differentiation of CTLs	0.02	Assumed	—
	Death rate of CTL precursors	0.02	0.005–0.15	[26]
	Proliferation of CTLs responsiveness	0.1	0.001–1	[26]
	Mortality rate or CTL effectors	0.1	0.005–0.15	[26]