Functional differential equations arise in many areas of science and technology: whenever a deterministic relationship involving some varying quantities and their rates of change in space and/or time (expressed as derivatives or differences) is known or postulated. This is illustrated in classical mechanics, where the motion of a body is described by its position and velocity as the time varies. In some cases, this differential equation (called an equation of motion) may be solved explicitly. In fact, differential equations play an important role in modelling virtually every physical, technical, biological, ecological, and epidemiological process, from celestial motion, to bridge design, to interactions between neurons, to interaction between species, to spread of diseases with a population, and so forth. Also many fundamental laws of chemistry can be formulated as differential equations and in economy differential equations are used to model the behavior of complex systems. However, the mathematical models can also take different forms depending on the time scale and space structure of the problem; it can be modeled by delay differential equations, difference equations, partial delay differential equations, partial delay difference equations, or the combination of these equations.

When necessary, random effects and sudden effects can also be considered in modelling problems. The mathematical theory of differential equations first developed, together with the sciences, where the equations had originated and where the results found applications. Differential and difference equations such as those used to solve real-life problems may not necessarily be directly solvable, that is, do not have closed form solutions. Only the simplest equations admit solutions given by explicit formulas; however, some properties of solutions of a given differential equation may be determined without finding their exact form. If a self-contained formula for the solution is not available, the solution may be numerically approximated using computers. In this case a recurrence relation is needed which is an equation that recursively defines a sequence: each term of the sequence is defined as a function of the preceding terms. A difference equation is a specific type of recurrence relations. Solving a recurrence relation means obtaining a closed form solution: a nonrecursive function.

However, diverse problems, sometimes originating in quite distinct scientific fields, may give rise to identical differential and difference equations. Whenever this happens, mathematical theory behind the equations can be viewed as a unifying principle behind diverse phenomena; see, for example, the books by Brauer and Castillo Chavize [1], Diekmann et al. [2], Gopalsamy [3], Gyori and Ladas [4], Kocic and Ladas [5], Kolmonovskii and Myshkis [6], Lakshmikantham et al. [7], May and Anderson [8], Murray [9], Sharkovsky et al. [10], and Wu [11].

A delay differential equation (DDE) is an equation for a function of a single variable, usually called time, in which the derivative of the function at a certain time is given in terms of the values of the function at earlier times. A functional equation () is an equation involving an unknown function for different argument values. The equations , , and so forth are examples of this type. The differences between the argument values of an unknown function and in a are called argument deviations. If all argument deviations are constants, then is called a difference equation. Combining the notions of differential and functional equations, we obtain the notion of functional differential equation () or equivalently differential equations with deviating argument. Thus, this is an equation concerning the unknown function and some of its derivatives for, in general, different argument values (present, past, or future). The order of a is the order of the highest derivative of the unknown function entering in the equation. So, a may be regarded as of order zero. Hence, the notion of generalizes all equations of mathematical analysis for functions of a continuous argument.

The qualitative study of functional differential equations and difference equations is a wide field in pure and applied mathematics, physics, meteorology, engineering, and population dynamics. All of these disciplines are concerned with the properties of these equations of various types. Pure mathematics focuses on the existence and uniqueness of solutions; for global existence and uniqueness theorems for differential equations, we refer to the books [6, 7, 12] and for basic theory of difference equations, we refer to the books [13]. On the other hand, applied mathematics emphasizes the rigorous justification of the qualitative behavior of solutions (oscillation, periodic orbits, persistence, permanence, stability, global attractivity, Hopf bifurcation, Floquet theory, control, synchronization, etc.) [2, 14, 15]. On the other hand the study of integral inequalities has received a lot of attention in the literature and has become a major field in pure and applied mathematics; we refer to the recent book [16].

The oscillation theory, stability theory, bifurcation theory, existence of periodic solutions and convergence of solutions as parts of the qualitative theory of differential and difference equations have been developed rapidly in the past thirty years and some interesting books have been written in these subjects. We refer the reader to the books [1721]. In this special issue we will consider some papers in all the above different areas and hope that the reader will find in this special issue some important results.

Cemil Tunç
Mouffak Benchohra
Bingwen Liu
Muhammad N. Islam
Samir H. Saker