Research Article

Comparative Study of Metaheuristics for the Curve-Fitting Problem: Modeling Neurotransmitter Diffusion and Synaptic Receptor Activation

Table 1

Parameter tuning of the selected metaheuristics.

Parameter values of GA

popSize 100, 200, 400
pcx 0.1, 0.5, 0.9
pm 0.01, 0.05, 0.1

Parameter values of DE

popSize 25, 50, 100
0.1, 0.5, 0.9
CR 0.1, 0.5, 0.9

Parameter values of Self-Adaptive DE

popSize 25, 50, 100
0.05, 0.1, 0.2
0.05, 0.1, 0.2

Parameter values of GODE

popSize 25, 50, 100
0.1, 0.5, 0.9
CR 0.1, 0.5, 0.9
godeProb 0.2, 0.4, 0.8

Parameter values of Solis and Wets

maxSuccess 2, 5, 10
maxFailed 1, 3, 5
adjustSuccess 2, 4, 6
adjustFailed 0.25, 0.5, 0.75
delta 0.6, 1.2, 2.4

Parameter values of MTS-LS1

(initial) SR 50% of the search space
(min) SR
adjustFailed 2, 3, 5
adjustMin 2.5, 5, 10
moveLeft 0.25, 0.5, 1
moveRight 0.25, 0.5, 1

Parameter values of CMA-ES

0.01, 0.1, 1
Active CMA no, yes
CMA-ES variant CMA-ES, IPOP-CMA-ES