Review Article
The Enzymatic Antioxidant System of Human Spermatozoa
Table 1
Characterization of peroxiredoxins.
| | Class | 2-Cys | Atypical 2-Cys | 1-Cys |
| | Isoform | PRDX1 to PRDX4 | PRDX5 | PRDX6 |
| | Substrates | H2O2, organic hydroperoxides | H2O2, organic hydroperoxides, ONOO− | H2O2, organic hydroperoxides, phospholipid hydroperoxides ONOO− |
| | PLA2 activity | No | No | Yes |
| | Sulfonated form | Yes | No | Yes |
| | Reductant system | | | | | Oxidized form | TRX/TRD | TRX/TRD | GSH/GSTs | | Sulfonated form | Sulfiredoxin/sestrin 1 | No | No |
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