Antiobesity and Hypolipidemic Activity of Moringa oleifera Leaves against High Fat Diet-Induced Obesity in Rats

Table 3

Effect of MEMOL on liver parameters and blood glucose in obese rats.

Parameter	Normal Control	HFD	Standard (3 mg/kg)	MEMOL; 200 mg/kg	MEMOL; 400 mg/kg
Total Cholesterol	75.180 ± 0.847	116.2±0.271^###	85.86±0.461^a∗∗∗	98.16±0.52^a∗∗	87.620 ± 0.543^a∗∗∗b∗
Triglycerides	217.68 ± 2.4	263.0±4.69^###	238.58±2.64^a∗∗∗	246.5±8.65^a∗∗∗	242.92±6.58^a∗∗∗bns
HDL (mg/dL)	69.6 ± 2.9	34.51±2.20^###	45.18±0.41^a∗∗∗	35.76±1.31^a∗∗∗	46.71±2.381^a∗∗∗
LDL (mg/dL)	46.71 ± 2.381	61.68±2.94^###	44.5±4.8^a∗∗∗	48.4±5.5^a∗∗∗	45.25±5.2^a∗∗∗
VLDL (mg/dL)	15.03 ± 0.169	38.22±4.6^###	17.172±0.092^a∗∗∗	23.5±6.6^a∗∗	19.6±0.105^a∗∗
SGOT (U/L)	31.4 ± 0.50	67.2±1.9^###	47.8±2.9^a∗∗∗	57.2±2.25^a∗∗∗	36.1±4.6^a∗∗∗
SGPT (U/L)	37.7 ± 0.6	76.2±2.02^###	45.6±1.5^a∗∗	54.3±3.7^a∗∗	42.8±5.4^a∗∗∗
Total Bilirubin (mg/dL)	0.5 ± 0.04	1.9±0.08^###	1.17±0.9^a∗∗∗	0.99±0.12^a∗∗∗bns	0.73±0.19^a∗∗∗b∗∗
Blood Glucose (mg/dL)	78.9 ± 3.4	94.1±4.9^###	86.0±6.0^a∗	81.3±3.3^a∗∗	73.2±5.2^a∗∗∗b∗∗

All values are expressed as Mean ± SEM, (𝑛=10), ^###𝑃<0.001 when compared with the normal control group, *𝑃<0.05; ***𝑃<0.001; **𝑃<0.01; ^ns𝑃>0.05. ^aversus High fat diet-induced obesity; ^bversus Standard control (one-way ANOVA, Tukey’s post hoc test, 𝑛=10 per group).