Wei Xia, Hung-Yao Hsu, Lingxue Kong, Allan Evans, Ryan Lee, "A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery", Applied Bionics and Biomechanics, vol. 4, Article ID 316561, 9 pages, 2007. https://doi.org/10.1080/11762320701403906
A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery
A liquid atomiser composed of a piezoelectric transducer and a metal plate with numerous micro-apertures is studied to identify the most influential factors on its atomising performance. The Taguchi method is employed in the experiment design and analysis of the study on how each factor acts in the atomising process. An optimal condition is determined for producing a stream of droplets. The study shows that the droplet size and the spraying velocity are suitable for ophthalmic drug delivery application, with an even distribution of the drug over most of the eyeball surface area due to the controllable cross-sectional area of the droplet stream. This greatly improves the treatment effectiveness and efficiency of eye therapy. Finally, a structure of the ophthalmic drug delivery system is proposed.
Copyright © 2007 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.