Research Article
Genomic Promoter Analysis Predicts Functional Transcription Factor Binding
Table 5
Prediction of in vivo occupancy by HNF1 and HNF4 by
BAM MEI analysis after removal of the unbound class from the analysis.
| | Predicted | | observed | HNF1
both | HNF1
hep | HNF1
panc | HNF4
both | HNF4 hep | HNF4 panc | Total (obs) | Sensitivity |
| | HNF1 both | 3 | 0 | 0 | 0 | 0 | 0 | 3 | 100% | | HNF1 hep | 0 | 12 | 0 | 0 | 4 | 2 | 18 | 100% | | HNF1 panc | 0 | 0 | 6 | 1 | 2 | 0 | 9 | 100% | | HNF4 both | 0 | 0 | 0 | 66 | 3 | 7 | 76 | 93% | | HNF4 hep | 0 | 0 | 0 | 1 | 74 | 9 | 84 | 85% | | HNF4 panc | 0 | 0 | 0 | 4 | 6 | 82 | 92 | 84% | | Total (pred) | 3 | 12 | 6 | 72 | 89 | 100 | 282 | | | Specificity | 100% | 98% | 99% | 95% | 95% | 95% | | |
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