Resource Review

EREM: Parameter Estimation and Ancestral Reconstruction by Expectation-Maximization Algorithm for a Probabilistic Model of Genomic Binary Characters Evolution

Figure 1

A fragment of a hypothetical input for a 4-species analysis. This is a segment of a multiple alignment of 4 orthologous genes. Notice the gap in one of the genes, designated by * for unknown character. Among the 10 sites in this alignment fragment, there are 6 unique patterns; . This portion of the alignment, therefore, contains 2 copies of , 2 copies of , 3 copies of , and one copy each from , , and .