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Advances in Bioinformatics
Volume 2011, Article ID 608295, 14 pages
Research Article

An Integrated Framework to Model Cellular Phenotype as a Component of Biochemical Networks

1Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Bluemle Life Sciences Building, 233 S. 10th Street, Philadelphia, PA 19107, USA
2School of Biomedical Engineering, Science and Health Systems, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104, USA
3American Association for Cancer Research, Cancer Discovery, 615 Chestnut Street, Philadelphia, PA 19106, USA

Received 23 June 2011; Accepted 26 August 2011

Academic Editor: Y. Van de Peer

Copyright © 2011 Michael Gormley et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Table 1: Goodness of fit of predicted values versus observed expression for the best fitting models. The goodness of fit of the original gene-centric models are listed in column 3. The goodness of fit of models with homologous gene approximations are listed in column 4.

  1. Supplementary Table