Gap Detection for Genome-Scale Constraint-Based Models
Figure 6
Searching for a gap-filling reaction is facilitated by a searchable and sortable database in MetModel GUI software. The initial model is unable to process adec. The reaction database in MetModel GUI has 10 reactions that involve adee. The KEGG database indicates that an enzyme for R_ADPT is encoded in the genome for C. neoformans and can be added to the model with confidence.
