Research Article

A High-Throughput Computational Framework for Identifying Significant Copy Number Aberrations from Array Comparative Genomic Hybridisation Data

Figure 3

Representative swatCGH copy number karyograms. The results shown are for chromosomes 7, 9, and 10, using data segmented by DNAcopy. Red bars at the bottom of each ideogram indicate regions of copy number loss, while cyan bars signify high-level loss. Green bars at the top of each ideogram represent regions of copy number gain, while yellow bars represent high-level gain. The purple bars on either side of each ideogram denote the CRIs identified by swatCGH analysis. Arrowheads locate MRIs identified as significant using amplitude based prioritization ( 𝑃 < 0 . 1 ).
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