Resource Review

BRASERO: A Resource for Benchmarking RNA Secondary Structure Comparison Algorithms

Figure 1

Overview of the BRASERO protocol. The benchmark (left part) is composed of positive (red) and negative (blue) sets of RNA sequences, that are folded and then compared to the reference set (right part). Each comparison tool can be parameterized to specify if it is distance based, in which case lower scores are better, or similarity based, in which case higher scores are better.
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