Advances in Bioinformatics / 2013 / Article / Alg 1

Research Article

Spectral Analysis on Time-Course Expression Data: Detecting Periodic Genes Using a Real-Valued Iterative Adaptive Approach

Algorithm 1

The pseudocode of the iterative process in RIAA.
Algorithm RIAA
Initialization
Use (6) to obtain the initial estimates and in .
The First Iteration
Obtain using (16) with parameters and given by . Obtain using (22). Using
and to drive the first weighted matrix by (15). Update estimate by (19) with = .
Updating Iteration
At the iteration, = , estimates and are iteratively updated in the same way
as the first iteration.
Termination
Terminate simply after 15 iterations ( = 15), or when the total changes in =
for , is extremely small, say, 0.005 , then = .

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