Research Article

MRMPath and MRMutation, Facilitating Discovery of Mass Transitions for Proteotypic Peptides in Biological Pathways Using a Bioinformatics Approach

Figure 5

(a) The user interface for MRMutation. A user can input a free text search of the Accession ID of a UniProt entry. (b) The results (truncated) of a search in the interface identified records with the keyword “p53.” (c) Clicking the first link results in the creation of a tryptic digest of the protein identified through Accession ID P04637. The mutated amino acid residues are highlighted in the tryptic peptide sequence, along with the m/z of the parent peptide ion.
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(c)