Advances in Bioinformatics / 2014 / Article / Tab 4

Research Article

Utilization of Boron Compounds for the Modification of Suberoyl Anilide Hydroxamic Acid as Inhibitor of Histone Deacetylase Class II Homo sapiens

Table 4

The inhibition constant (p) of ligand binding with HDAC class II Homo sapiens.

LigandInhibition constant (p)
HDAC4HDAC5HDAC6HDAC7HDAC9HDAC10

Nova2 (9058064-6)18,8221,0921,4422,8218,3917,49
Nova2 (95752-88-8)13,3023,0721,0320,5019,4818,92
Nova2 (88765-82-6)17,2121,2920,5418,5117,6316,99
Nova2 (Unique10)17,3321,2320,0919,4217,7715,23
Nova2 (16876-27-0)12,3620,2018,8617,7118,0716,64
Nova2 (513246-99-6)16,5320,8119,6819,4718,1515,85
Nova2 (Unique80)16,1318,2119,5317,8617,0715,18
Nova2 (279262-23-6)16,1320,0118,9719,7317,6715,07
SAHA10,1512,5911,1910,5911,8011,20
TSA10,6811,0810,709,8410,409,48