Secondary Structure Preferences of Mn²⁺ Binding Sites in Bacterial Proteins

Table 2

Probabilities of amino acids and secondary structure elements occurrence near the aspartic acid binding Mn⁺². Significantly overrepresented amino acids and secondary structure elements are written in bold font; significantly underrepresented ones are written in italic font.

	Position
	−5	−4	−3	−2	−1	0	+1	+2	+3	+4	+5
Secondary structure elements
Alpha helix	0.1796	0.2099	0.2427	0.2757	0.3284	0.3450	0.3750	0.3923	0.4062	0.4153	0.4229
Helix 3/10	0.1435	0.1510	0.1379	0.1846	0.1902	0.3374	0.3890	0.5680	0.5579	0.5497	0.5340
Beta strand	0.7168	0.7501	0.7617	0.7797	0.7586	0.7487	0.6100	0.5517	0.5250	0.4016	0.4096
Random coil	0.5246	0.4327	0.4106	0.4193	0.4908	0.5285	0.5748	0.5660	0.5771	0.6264	0.6217
Amino acid residues
Gly	0.6370	0.5558	0.3270	0.4731	0.6460		0.5860	0.4783	0.6672	0.4998	0.5666
Ala	0.4842	0.3034	0.4950	0.3750	0.4514		0.5373	0.3277	0.5514	0.3597	0.5503
Arg	0.2299	0.3577	0.1282	0.4743	0.1549		0.1403	0.4793	0.1268	0.5027	0.5420
Pro	0.5154	0.3658	0.1608	0.3739	0.2431		0.2746	0.2586	0.4131	0.6845	0.5039
Asp	0.5393	0.4436	0.3350	0.6726	0.5070		0.4226	0.6602	0.5108	0.6133	0.5779
Glu	0.2582	0.3646	0.1760	0.0657	0.4343		0.4201	0.3424	0.4847	0.4610	0.4299
Ser	0.4719	0.5163	0.4048	0.4725	0.6910		0.6380	0.5689	0.5003	0.5770	0.6512
Thr	0.3882	0.1855	0.4723	0.6461	0.5266		0.6485	0.4065	0.5931	0.5352	0.4776
His	0.4805	0.6318	0.6570	0.7083	0.1879		0.7599	0.7252	0.7558	0.6928	0.5135
Gln	0.4885	0.3112	0.3250	0.4054	0.3304		0.5678	0.3378	0.5758	0.4960	0.5348
Leu	0.6035	0.6947	0.6182	0.4934	0.5553		0.4201	0.5345	0.5134	0.4761	0.4477
Val	0.6213	0.5765	0.7197	0.4899	0.6191		0.5851	0.4018	0.4680	0.4045	0.4777
Cys	0.6184	0.5520	0.5529	0.4680	0.7590		0.4053	0.5605	0.5840	0.3918	0.3335
Trp	0.0000	0.0000	0.4445	0.4243	0.5059		0.4874	0.7362	0.0000	0.2677	0.6925
Phe	0.2463	0.4276	0.5089	0.4954	0.6110		0.5702	0.5567	0.4872	0.4516	0.4760
Tyr	0.4526	0.5446	0.5939	0.5095	0.3509		0.3762	0.3193	0.5080	0.4889	0.3463
Met	0.5173	0.3223	0.6056	0.6057	0.4699		0.5728	0.5943	0.2946	0.6626	0.4124
Ile	0.6001	0.6224	0.7370	0.5852	0.4886		0.4826	0.4942	0.4968	0.4914	0.3347
Asn	0.4551	0.5931	0.0000	0.5943	0.3750		0.3671	0.6858	0.4067	0.4742	0.4787
Lys	0.3930	0.3637	0.2196	0.2408	0.0000		0.1701	0.5178	0.1870	0.2516	0.4428