Secondary Structure Preferences of Mn²⁺ Binding Sites in Bacterial Proteins

Table 3

Probabilities of amino acids and secondary structure elements occurrence near the histidine binding Mn⁺². Significantly overrepresented amino acids and secondary structure elements are written in bold font; significantly underrepresented ones are written in italic font.

	Position
	−5	−4	−3	−2	−1	0	+1	+2	+3	+4	+5
Secondary structure
Alpha helix	0.3529	0.3658	0.3722	0.3875	0.3926	0.3743	0.3520	0.4060	0.4216	0.4283	0.4377
Helix 3/10	0.1925	0.1996	0.1087	0.3760	0.4942	0.6047	0.6233	0.5132	0.5301	0.5028	0.5619
Beta strand	0.6909	0.7072	0.6777	0.6241	0.6109	0.6085	0.5758	0.4659	0.4537	0.4593	0.5050
Random coil	0.4714	0.4269	0.4756	0.5203	0.5102	0.5062	0.5415	0.5858	0.5881	0.5867	0.5562
Amino acid residues
Gly	0.6023	0.5387	0.6237	0.4542	0.6047		0.5111	0.5110	0.4700	0.5090	0.5105
Ala	0.4429	0.4286	0.3014	0.6146	0.3698		0.6546	0.3897	0.4648	0.4391	0.3511
Arg	0.5318	0.4737	0.4076	0.2917	0.4558		0.3026	0.4410	0.4804	0.3694	0.5197
Pro	0.4229	0.4390	0.5047	0.2392	0.4987		0.3511	0.3794	0.5078	0.6874	0.5455
Asp	0.3510	0.6344	0.5209	0.6087	0.6750		0.2911	0.5713	0.4739	0.4474	0.5105
Glu	0.3804	0.4838	0.5212	0.5326	0.3849		0.4055	0.3864	0.5007	0.4144	0.6324
Ser	0.4728	0.5826	0.4980	0.5494	0.5863		0.7419	0.0978	0.5219	0.5802	0.5573
Thr	0.4240	0.5182	0.5166	0.5641	0.4518		0.5387	0.6706	0.4724	0.3971	0.6449
His	0.5489	0.5257	0.5404	0.7368	0.4190		0.6764	0.8082	0.2810	0.6637	0.5514
Gln	0.5220	0.2021	0.4725	0.3245	0.1381		0.3898	0.5475	0.5442	0.4031	0.5182
Leu	0.4046	0.5090	0.5548	0.4323	0.5618		0.4203	0.4750	0.4355	0.4289	0.4841
Val	0.5500	0.4548	0.6161	0.4453	0.3470		0.2674	0.3332	0.3967	0.2995	0.4563
Cys	0.8949	0.6196	0.0000	0.6837	0.5906		0.2911	0.6570	0.6209	0.6568	0.5891
Trp	0.3405	0.4872	0.2416	0.7546	0.7121		0.7853	0.6885	0.6417	0.7782	0.2906
Phe	0.4969	0.3161	0.4387	0.4013	0.3441		0.4560	0.4380	0.7076	0.4738	0.1153
Tyr	0.6653	0.3878	0.4100	0.5355	0.5442		0.5640	0.6372	0.6323	0.6707	0.2106
Met	0.5390	0.5246	0.7035	0.5043	0.5459		0.4721	0.2583	0.6417	0.3647	0.3892
Ile	0.6665	0.6516	0.4374	0.2859	0.5639		0.5630	0.5199	0.4174	0.4135	0.5182
Asn	0.5579	0.2262	0.4300	0.5439	0.6292		0.3194	0.5999	0.4114	0.7416	0.4828
Lys	0.3661	0.4821	0.0886	0.1288	0.3034		0.3575	0.1932	0.5771	0.2601	0.5197