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Advances in Bioinformatics
Volume 2015, Article ID 198363, 13 pages
http://dx.doi.org/10.1155/2015/198363
Review Article

A Review of Feature Selection and Feature Extraction Methods Applied on Microarray Data

Department of Computing, Imperial College London, London SW7 2AZ, UK

Received 25 March 2015; Accepted 18 May 2015

Academic Editor: Huixiao Hong

Copyright © 2015 Zena M. Hira and Duncan F. Gillies. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We summarise various ways of performing dimensionality reduction on high-dimensional microarray data. Many different feature selection and feature extraction methods exist and they are being widely used. All these methods aim to remove redundant and irrelevant features so that classification of new instances will be more accurate. A popular source of data is microarrays, a biological platform for gathering gene expressions. Analysing microarrays can be difficult due to the size of the data they provide. In addition the complicated relations among the different genes make analysis more difficult and removing excess features can improve the quality of the results. We present some of the most popular methods for selecting significant features and provide a comparison between them. Their advantages and disadvantages are outlined in order to provide a clearer idea of when to use each one of them for saving computational time and resources.