Research Article

A Highly Conserved GEQYQQLR Epitope Has Been Identified in the Nucleoprotein of Ebola Virus by Using an In Silico Approach

Table 3

Linear B-cell epitope, antigenic regions, and surface accessible epitopes predicted from the conserved region of nucleoprotein (NP).

PeptideLength

BepiPred analysis (linear B-cell epitope)
SSGKN5
AMPEEETTEANA12
TAWQ4
HDANDAV7
KVKN4
KHGEYA6
AHGS4
VGEQYQQLREAATEAEKQLQQYAESR26
LDDQ4
EISF4

IEDB analysis (antigenic sites)
KRLEELLPAVSSG13
GQFLSFASLFLPKLVVGEKACLEK 55
VQRQIQVHAEQGLIQYPTAWQSV
GHMMVIFR
LIKFLLIHQ 9
NDAVISNSVAQA12
FSGLLIVKTVLDHILQ16
GVRLHPLARTA11
SFKAALSSLAKHGEYAPFARLLNLS25
HGLFPQLSAIALGVATA17
GSTLAGVNVGEQYQQLRE18
LDHLGL6

Surface accessible epitope
MPEEETTE8
AKVKNE6
GEQYQQLR8
AATEAEKQLQQYAESREL18
FHQKKNE7
LRKERL6