Local Mutational Pressures in Genomes of Zaire Ebolavirus and Marburg Virus

Table 5

Directions of mutational pressure in coding regions and their fragments for Zaire ebolavirus according to the “VVTAK VarInvar” algorithm results. Nucleotide usages in invariable and stable twofold degenerated sites from third codon positions are compared.

Gene/fragment	NP; part 1	NP; part 2	VP35	VP40	GP; part 1	GP; part 2	GP; part 3	VP30	VP24	LP
Cytosine usage
Direction
Invariable	19,80%	25,32%	20,87%	25,56%	31,48%	37,50%	27,91%	14,41%	25,29%	18,08%
Stable	18,75%	27,87%	19,29%	23,97%	31,22%	39,64%	27,79%	14,02%	23,97%	19,34%
Guanine usage
Direction
Invariable	24,75%	23,38%	22,61%	26,67%	18,52%	12,50%	18,60%	21,62%	18,39%	16,67%
Stable	25,69%	21,87%	24,87%	27,74%	21,36%	11,82%	20,34%	22,01%	19,16%	17,31%
Uracil usage
Direction
Invariable	27,72%	26,62%	26,96%	32,22%	24,07%	21,43%	32,56%	28,83%	24,14%	35,92%
Stable	28,26%	27,30%	25,75%	29,88%	23,46%	22,13%	28,21%	26,29%	26,03%	34,65%
Adenine usage
Direction
Invariable	27,72%	24,68%	29,57%	15,56%	25,93%	28,57%	20,93%	35,14%	32,18%	29,34%
Stable	27,30%	22,96%	30,09%	18,41%	23,95%	26,42%	23,66%	37,68%	30,84%	28,69%