Bioinformatics Approach for Prediction of Functional Coding/Noncoding Simple Polymorphisms (SNPs/Indels) in Human BRAF Gene

Table 4

Functional SNPs predicted by double tools.

Protein ID	Amino acid change	SIFT prediction	Score	PolyPhen-2 prediction	Score	SNAP2 prediction	Score
ENSP00000419060	R70I	Damaging	0	Benign	0.311	Effect	34
ENSP00000288602	V600M	Damaging	0	Probably damaging	0.99	Neutral
ENSP00000288602	L597V	Damaging	0	Probably damaging	0.862	Neutral	0
ENSP00000419060	L205V	Damaging	0	Probably damaging	0.995	Neutral
ENSP00000419060	V208M	Damaging	0.03	Probably damaging	0.996	Neutral
ENSP00000418033	H2Q	Damaging	0	Probably damaging	0.998	Neutral