Research Article

Multiple Linear Regression for Reconstruction of Gene Regulatory Networks in Solving Cascade Error Problems

Table 5

Characteristics of the datasets tested in the experiment and the AUROC results.

Set 1Set 2Set 3

Number of cascade motif genes in the tested datasets363360160
Number of random genes in the tested datasets
(not redundant with cascade motif genes)
397533255
Total number of tested genes760893415
Total number of possible edges576,840796,556171,810
Total number of correct prediction (CORRECT_PRED)11910825
Total number of incorrect prediction27,526253170,985

AUROC0.5110.5020.662
Average: 0.5584

Note:
() Cascade motif genes (italic text) are referring to the gene itself. This is not similar to cascade motif.
() Number of cascade motif genes in the tested datasets are obtained by comparing the cascade motifs genes with the genes in the datasets.
() Total number of possible edges = Total number of tested genes × (Total number of tested genes – 1).