Table 5: The gene coexpression, shared domain, and interaction with MEFV gene network.

Gene 1Gene 2WeightNetwork group

PF4CEBPB0.01083Co-expression
NLRP14MEFV0.014663Co-expression
EPXPADI40.01094Co-expression
CASP1PYCARD0.012291Co-expression
TINAGL1MEFV0.021529Co-expression
ZNF747MEFV0.032075Co-expression
ZNF747TINAGL10.01915Co-expression
EPXMEFV0.019982Co-expression
EPXZNF7470.01848Co-expression
MRPL44MEFV0.02576Co-expression
RPL27AMEFV0.023047Co-expression
TCTN2MEFV0.02049Co-expression
TCTN2ZNF7470.021219Co-expression
TCTN2RPL27A0.019574Co-expression
ZNF528RPL27A0.021843Co-expression
ZNF528TCTN20.020287Co-expression
PF4TINAGL10.018596Co-expression
PF4EPX0.016477Co-expression
CASP1PYCARD0.005924Co-expression
NLRP3CEBPB0.01342Co-expression
CASP1PYCARD0.005896Co-expression
AZU1MEFV0.01109Co-expression
MAP1LC3CNLRP140.011062Co-expression
PADI4MEFV0.003094Co-expression
AZU1MEFV0.003152Co-expression
AZU1PADI40.004853Co-expression
ZNF747MEFV0.004908Co-expression
PADI4MEFV0.023362Co-expression
AZU1MEFV0.012616Co-expression
AZU1PADI40.014322Co-expression
NLRP14MEFV0.01623Co-expression
EPXPADI40.01024Co-expression
EPXAZU10.007038Co-expression
ZNF528MEFV0.039375Co-expression
PF4MEFV0.017902Co-expression
PF4AZU10.012247Co-expression
PF4EPX0.007715Co-expression
TINAGL1MEFV0.027084Co-expression
MRPL44MEFV0.011927Co-expression
TCTN2MEFV0.014192Co-expression
TCTN2TINAGL10.014867Co-expression
TCTN2ZNF7470.010889Co-expression
TCTN2MAP1LC3C0.006994Co-expression
TCTN2MRPL440.010528Co-expression
ZNF528TCTN20.012167Co-expression
RPL27AMEFV0.016846Co-expression
TCTN2RPL27A0.018021Co-expression
CASP1PSTPIP10.009518Co-expression
EPXAZU10.01909Co-localization
PADI4MEFV0.012301Co-localization
PADI4PSTPIP10.008748Co-localization
AZU1MEFV0.011852Co-localization
AZU1PSTPIP10.008052Co-localization
AZU1PADI40.006025Co-localization
EPXMEFV0.011933Co-localization
EPXPSTPIP10.008374Co-localization
EPXPADI40.006323Co-localization
EPXAZU10.006061Co-localization
FBXO9MEFV0.022287Co-localization
FBXO9PADI40.009957Co-localization
FBXO9AZU10.009656Co-localization
FBXO9EPX0.009948Co-localization
PF4MEFV0.012063Co-localization
PF4PSTPIP10.007583Co-localization
PF4PADI40.005603Co-localization
PF4AZU10.005356Co-localization
PF4EPX0.005651Co-localization
PF4FBXO90.009449Co-localization
CEBPBMEFV0.159581Pathway
RELAMEFV0.078321Pathway
PSTPIP1MEFV0.953023Pathway
PYCARDMEFV0.037199Pathway
CASP1PYCARD0.037199Pathway
CASP1MEFV0.469715Physical Interactions
NLRP3PYCARD0.570819Physical Interactions
PYCARDMEFV0.03673Physical Interactions
PYCARDPSTPIP10.028273Physical Interactions
CASP1PYCARD0.017772Physical Interactions
CASP1CEBPB0.010941Physical Interactions
RELACEBPB0.00247Physical Interactions
COG5MEFV0.211887Physical Interactions
NLRP3MEFV0.111467Physical Interactions
MAP1LC3CMEFV0.104412Physical Interactions
PYCARDMEFV0.292858Physical Interactions
NLRP3PYCARD0.189095Physical Interactions
PSTPIP1MEFV0.260595Physical Interactions
PYCARDMEFV0.204673Physical Interactions
CASP1PYCARD0.042335Physical Interactions
RELACEBPB0.007591Physical Interactions
COG5MEFV0.387501Physical Interactions
NLRP3PYCARD0.304828Physical Interactions
NLRP3PYCARD1Predicted
PYCARDMEFV0.455503Predicted
CASP1PYCARD0.043769Predicted
RELACEBPB0.024601Predicted
NLRP3PYCARD0.25852Predicted
CASP1CEBPB0.445416Predicted
CASP1CEBPB0.707107Predicted
PYCARDMEFV0.00952Shared protein domains
CASP1PYCARD0.013543Shared protein domains
NLRP3MEFV0.009339Shared protein domains
NLRP3PYCARD0.018527Shared protein domains
NLRP14MEFV0.009512Shared protein domains
NLRP14PYCARD0.018871Shared protein domains
NLRP14NLRP30.036989Shared protein domains
ZNF528ZNF7470.002699Shared protein domains
PYCARDMEFV0.011528Shared protein domains
CASP1PYCARD0.031451Shared protein domains
NLRP3MEFV0.009427Shared protein domains
NLRP3PYCARD0.015448Shared protein domains
NLRP14MEFV0.009815Shared protein domains
NLRP14PYCARD0.016085Shared protein domains
NLRP14NLRP30.019774Shared protein domains
ZNF528ZNF7470.002759Shared protein domains