Advances in Bioinformatics / 2019 / Article / Tab 5 / Research Article
Novel Deleterious nsSNPs within MEFV Gene that Could Be Used as Diagnostic Markers to Predict Hereditary Familial Mediterranean Fever: Using Bioinformatics Analysis Table 5 The gene coexpression, shared domain, and interaction with MEFV gene network.
Gene 1 Gene 2 Weight Network group PF4 CEBPB 0.01083 Co-expression NLRP14 MEFV 0.014663 Co-expression EPX PADI4 0.01094 Co-expression CASP1 PYCARD 0.012291 Co-expression TINAGL1 MEFV 0.021529 Co-expression ZNF747 MEFV 0.032075 Co-expression ZNF747 TINAGL1 0.01915 Co-expression EPX MEFV 0.019982 Co-expression EPX ZNF747 0.01848 Co-expression MRPL44 MEFV 0.02576 Co-expression RPL27A MEFV 0.023047 Co-expression TCTN2 MEFV 0.02049 Co-expression TCTN2 ZNF747 0.021219 Co-expression TCTN2 RPL27A 0.019574 Co-expression ZNF528 RPL27A 0.021843 Co-expression ZNF528 TCTN2 0.020287 Co-expression PF4 TINAGL1 0.018596 Co-expression PF4 EPX 0.016477 Co-expression CASP1 PYCARD 0.005924 Co-expression NLRP3 CEBPB 0.01342 Co-expression CASP1 PYCARD 0.005896 Co-expression AZU1 MEFV 0.01109 Co-expression MAP1LC3C NLRP14 0.011062 Co-expression PADI4 MEFV 0.003094 Co-expression AZU1 MEFV 0.003152 Co-expression AZU1 PADI4 0.004853 Co-expression ZNF747 MEFV 0.004908 Co-expression PADI4 MEFV 0.023362 Co-expression AZU1 MEFV 0.012616 Co-expression AZU1 PADI4 0.014322 Co-expression NLRP14 MEFV 0.01623 Co-expression EPX PADI4 0.01024 Co-expression EPX AZU1 0.007038 Co-expression ZNF528 MEFV 0.039375 Co-expression PF4 MEFV 0.017902 Co-expression PF4 AZU1 0.012247 Co-expression PF4 EPX 0.007715 Co-expression TINAGL1 MEFV 0.027084 Co-expression MRPL44 MEFV 0.011927 Co-expression TCTN2 MEFV 0.014192 Co-expression TCTN2 TINAGL1 0.014867 Co-expression TCTN2 ZNF747 0.010889 Co-expression TCTN2 MAP1LC3C 0.006994 Co-expression TCTN2 MRPL44 0.010528 Co-expression ZNF528 TCTN2 0.012167 Co-expression RPL27A MEFV 0.016846 Co-expression TCTN2 RPL27A 0.018021 Co-expression CASP1 PSTPIP1 0.009518 Co-expression EPX AZU1 0.01909 Co-localization PADI4 MEFV 0.012301 Co-localization PADI4 PSTPIP1 0.008748 Co-localization AZU1 MEFV 0.011852 Co-localization AZU1 PSTPIP1 0.008052 Co-localization AZU1 PADI4 0.006025 Co-localization EPX MEFV 0.011933 Co-localization EPX PSTPIP1 0.008374 Co-localization EPX PADI4 0.006323 Co-localization EPX AZU1 0.006061 Co-localization FBXO9 MEFV 0.022287 Co-localization FBXO9 PADI4 0.009957 Co-localization FBXO9 AZU1 0.009656 Co-localization FBXO9 EPX 0.009948 Co-localization PF4 MEFV 0.012063 Co-localization PF4 PSTPIP1 0.007583 Co-localization PF4 PADI4 0.005603 Co-localization PF4 AZU1 0.005356 Co-localization PF4 EPX 0.005651 Co-localization PF4 FBXO9 0.009449 Co-localization CEBPB MEFV 0.159581 Pathway RELA MEFV 0.078321 Pathway PSTPIP1 MEFV 0.953023 Pathway PYCARD MEFV 0.037199 Pathway CASP1 PYCARD 0.037199 Pathway CASP1 MEFV 0.469715 Physical Interactions NLRP3 PYCARD 0.570819 Physical Interactions PYCARD MEFV 0.03673 Physical Interactions PYCARD PSTPIP1 0.028273 Physical Interactions CASP1 PYCARD 0.017772 Physical Interactions CASP1 CEBPB 0.010941 Physical Interactions RELA CEBPB 0.00247 Physical Interactions COG5 MEFV 0.211887 Physical Interactions NLRP3 MEFV 0.111467 Physical Interactions MAP1LC3C MEFV 0.104412 Physical Interactions PYCARD MEFV 0.292858 Physical Interactions NLRP3 PYCARD 0.189095 Physical Interactions PSTPIP1 MEFV 0.260595 Physical Interactions PYCARD MEFV 0.204673 Physical Interactions CASP1 PYCARD 0.042335 Physical Interactions RELA CEBPB 0.007591 Physical Interactions COG5 MEFV 0.387501 Physical Interactions NLRP3 PYCARD 0.304828 Physical Interactions NLRP3 PYCARD 1 Predicted PYCARD MEFV 0.455503 Predicted CASP1 PYCARD 0.043769 Predicted RELA CEBPB 0.024601 Predicted NLRP3 PYCARD 0.25852 Predicted CASP1 CEBPB 0.445416 Predicted CASP1 CEBPB 0.707107 Predicted PYCARD MEFV 0.00952 Shared protein domains CASP1 PYCARD 0.013543 Shared protein domains NLRP3 MEFV 0.009339 Shared protein domains NLRP3 PYCARD 0.018527 Shared protein domains NLRP14 MEFV 0.009512 Shared protein domains NLRP14 PYCARD 0.018871 Shared protein domains NLRP14 NLRP3 0.036989 Shared protein domains ZNF528 ZNF747 0.002699 Shared protein domains PYCARD MEFV 0.011528 Shared protein domains CASP1 PYCARD 0.031451 Shared protein domains NLRP3 MEFV 0.009427 Shared protein domains NLRP3 PYCARD 0.015448 Shared protein domains NLRP14 MEFV 0.009815 Shared protein domains NLRP14 PYCARD 0.016085 Shared protein domains NLRP14 NLRP3 0.019774 Shared protein domains ZNF528 ZNF747 0.002759 Shared protein domains
