Peptide-Protein Interaction Studies of Antimicrobial Peptides Targeting Middle East Respiratory Syndrome Coronavirus Spike Protein: An In Silico Approach

Table 1

The table shows the filtering of antimicrobial peptides from various sources based on length, WWIHS, iHMM, and net charge.

S.No	Peptide	APD3 ID	Definition	Length	WWIHS	iHHM	Net charge
1	KTCENLADTFRGPCFATSNC	AP00532	Lunatusin	20	1.8	2.62	0
2	GLFVGVLAKVAAHVVPAIAEHF	AP00260	Maculatin 1.1	22	1.29	3.26	1
3	GIGKFLHSAGKFGKAFVGEIMKS	AP00771	Magainin 1	23	1.34	7.19	3
4	GIGKFLHSAKKFGKAFVGEIMNS	AP00144	Magainin 2	23	0.93	7.1	3
5	GEGFLGMLLHGVGHAIHGLIHGK	AP02663	Piscidins	23	1.26	4.72	0
6	GLRSKIWLWVLLMIWQESNKFKKM	AP00764	Dermaseptin-S9	24	6.07	2.95	4
7	FLPVLAGIAAKVVPALFCKITKKC	AP00074	Brevinin-1	24	1.31	3.48	4
8	GWGSFFKKAAHVGKHVGKAALTHYL	AP00166	Pleurocidin	25	0.37	7.49	4
9	FFGWLIRGAIHAGKAIHGLIHRRRH	AP00340	Chrysophsin-2	25	0.02	5.97	0
10	ALWMTLLKKVLKAAAKAALNAVLVGANA	AP00160	Dermaseptin-S4	28	0.92	4.71	4
11	GLPVCGETCVGGTCNTPGCTCSWPVCTRN	AP00729	Kalata B1	29	1.94	3.64	0
12	GAFGNFLKGVAKKAGLKILSIAQCKLSGTC	AP01644	Brevinin-2-RN1	30	0.62	1.97	5
13	GWFKKAWRKVKNAGRRVLKGVGIHYGVGLI	AP00692	Hagfish cathelicidin	30	0.24	6.41	8
14	GSVLNCGETCLLGTCYTTGCTCNKYRVCTKD	AP00730	Kalata B8	31	2.47	2.06	1
15	RRCICTTRTCRFPYRRLGTCIFQNRVYTFCC	AP00174	Guinea pig neutrophil	31	2.16	2.06	7
16	ACYCRIGACVSGERLTGACGLNGRIYRLCCR	AP00225	RatNP-4 rat defensin,	31	2.43	2.58	4
17	GVIPCGESCVFIPCISTLLGCSCKNKVCYRN	AP00275	Circulin B	31	2.44	3.23	2
18	GVIPCGESCVFIPCISAAIGCSCKNKVCYRN	AP01022	Cycloviolin A	31	1.43	2.52	2
19	KIPCGESCVWIPCVTSIFNCKCKENKVCYHD	AP01061	Circulin D	31	1.27	5.43	1
20	GSIPACGESCFKGKCYTPGCSCSKYPLCAKN	AP01065	Cycloviolacin O14	31	0.73	1.48	3
21	CGESCVFIPCITTVLGCSCSIKVCYKNGSIP	AP02571	Cycloviolacin VY1	31	3.15	2.77	1
22	ATCYCRTGRCATRESLSGVCEISGRLYRLCCR	AP00180	Human defensin 5	32	1.39	3.83	4
23	AFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL	AP00181	Human defensin 6	32	3.82	2.56	2
24	VTCYCRRTRCGFRERLSGACGYRGRIYRLCCR	AP00222	RatNP-1 rat defensin	32	1.02	4.29	8
25	VTCYCRSTRCGFRERLSGACGYRGRIYRLCCR	AP00223	RatNP-2 rat defensin	32	1.7	4.01	7
26	GFFALIPKIISSPLFKTLLSAVGSALSSSGEQE	AP00641	Pardaxin 1	33	4.19	0.2	0
27	VCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRV	AP00179	Human neutrophil peptide-4	33	3.28	1.54	4
28	DFASCHTNGGICLPNRCPGHMIQIGICFRPRVKCCRSW	AP00036	Bovine beta-defensin 1	38	0.22	4.72	4
29	GFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY	AP00549	Plectasin	40	2.11	3.67	1
30	GLPQDCERRGGFCSHKSCPPGIGRIGLCSKEDFCCRSRWYS	AP00744	Chicken AvBD5	41	0.93	3.26	3
31	SPIHACRYQRGVCIPGPCRWPYYRVGSCGSGLKSCCVRNRWA	AP00742	Chicken AvBD6	42	0.58	2.64	7
32	KYYGNGVSCNKKGCSVDWGKAIGIIGNNSAANLATGGAAGWKS	AP00846	Mundticin KS	43	0.83	2.1	4
33	QEAQSVACTSYYCSKFCGSAGCSLYGCYLLHPGKICYCLHCSR	AP01788	Myticin C	43	4.62	0.95	2
34	VSFPWSCAALSGVCRQGACLPSELYFGPLGCGKGSLCCVSYFL	AP02830	Channel catfish beta defensin	43	8.81	2.3	1
35	KTCMTKKEGWGRCLIDTTCAHSCRKYGYMGGKCQGITRRCYCLLNC	AP01356	Cp-thionin II	46	0.39	2.59	7
36	FFLLFLQGAAGNSVLCRIRGGRCHVGSCHFPERHIGRCSGFQACCIRTWG	AP02148	Apl-AvBD16	50	3.26	5.26	5
37	LFGSVKAWFKGAKKGFQDYRYQKDMAKMNKRYGPNWQQRGGQEPPADAQANDQPP	AP02733	Piscidin 6	55	2.93	6.41	5