Antimicrobial Photodynamic Activity of Phthalocyanine Derivatives

Table 3

Concentration, target microbes, efficacy reduction, and inhibition of different derivatives of phthalocyanine.

Pc	Concentration	Target microbes	Efficacy reduction	Inhibition zone/% reduction	Ref.
Zinc-tetra(4-carboxyphenyl)Pc	39.5 μg/mL	Escherichia coli		100.00%	[19]
Zinc-tetra(4-carboxyphenyl)Pc	22.02 μg/L	Enterococcus faecalis		32.91%	[19]
Zinc-tetra(4-carboxyphenyl)Pc	10.43 μg/mL	Klebsiella pneumonia		100.00%	[19]
Zinc-tetra(4-carboxyphenyl)Pc	22.48 μg/mL	Pseudomonas aeruginosa		12.25%	[19]
Zinc-tetra(4-carboxyphenyl)Pc	16.03 μg/Ml	Staphylococcus aureus		72.22%	[19]
Cobalt 2, 9, 16, 23-tetra-phenyliminophthalocyanine	500 ppm	Xanthomonas campestris		16 mm	[20]
		Xanthomonas citri		17 mm
Copper 2, 9, 16, 23-tetra-phenyliminophthalocyanine	500 ppm	Xanthomonas campestris		19 mm	[20]
		Xanthomonas citri		19 mm
Nickel 2, 9, 16, 23-tetra-phenyliminophthalocyanine	500 ppm	Xanthomonas campestris		18 mm	[20]
		Xanthomonas citri		18 mm
Zinc 2, 9, 16, 23-tetra-phenyliminophthalocyanine	500 ppm	Xanthomonas campestris		19 mm	[20]
		Xanthomonas citri		19 mm
Zinc phthalocyanine(neutral)	2 mM	Aeromonas hydrophila	<0.5 log		[21]
Tetra zinc (II)phthalocyanine	64 ng/mL	Staphylococcus aureus	5-6 logs		[21]
Cationic zinc(II)phthalocyanine substituted with triamino	13 nM	Staphylococcus aureus	4 logs		[21]
Neutral uncharged Zn(II)pyridyloxyphthalocyanine	10 µM	Escherichia coli	0.5 logs		[21]
Chromium (III) phthalocyanine; chloride complex		Escherichia coli		12 mm	[22]
Chromium (III) phthalocyanine; chloride complex		Pseudomonas aeruginosa		9 mm	[22]
Chromium (III) phthalocyanine; chloride complex		Staphylococcus aureus		10 mm	[22]
Chromium (III) phthalocyanine; chloride complex		Bacillus cereus		11 mm	[22]
2,9,16,23-Tetra-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]benzamido-nickelphthalocyanines	40 μg/mL	Staphylococcus aureus		23 mm	[23]
		Pseudomonas aeruginosa		27 mm
		Klebsiella pneumonia		28 mm
2,9,16,23-Tetra-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]benzamido-cobalt phthalocyanine	40 μg/mL	Staphylococcus aureus		25 mm	[23]
		Pseudomonas aeruginosa		26 mm
		Klebsiella pneumoniae		29 mm
2,9,16,23-Tetra-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]benzamido-cobalt phthalocyanine	40 μg/mL	Staphylococcus aureus		26 mm	[23]
		Pseudomonas aeruginosa		27 mm
		Klebsiella pneumoniae		28 mm
Zinc phthalocyanine with sulphamidic substituents	50 mg/100 ml	Pseudomonas aeruginosa	6 log		[24]
		Escherichia coli	4 log
		Enterococcus faecalis	<0.5 log
Tris,19,27-(1,2-diethylaminoethylthiol)-2-(captopril) phthalocyanines Zn	20 uM	Escherichia coli		90%	[16]
Tris,19,27-(1,2-diethylaminoethylthiol)-2-(captopril) phthalocyanines Zn conjugated to silver nanoparticles	20 uM	Escherichia coli		95%	[16]