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Analytical Cellular Pathology
Volume 21 (2000), Issue 3-4, Pages 149-159

A Telepathology Based Virtual Reference and Certification Centre for DNA Image Cytometry

G. Haroske,1 Francoise Giroud,2 K. D. Kunze,3 and W. Meyer3

1Institute of Pathology, Dresden‐Friedrichstadt General Hospital, Germany
2Institute Albert Bonniot, Faculté de Médecine, Université Joseph Fourier, Grenoble, France
3Institute of Pathology, Dresden University of Technology, Germany

Copyright © 2000 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


An increasing need for flexible consultation between pathologists, including the application of fast evolving supplementary technologies, has been identified during the last years. Although pathology is already one of the most advanced application of telemedicine there is more to come from the fast evolution towards computerized microscope image analysis: A reproducible quantification of measurable descriptors of the lesions in cells and tissues (so‐called biological markers) is an indispensable adjunct to routine diagnostic application. Among such quantitative methods DNA image cytometry is increasingly applied by pathologists for assistance in diagnostics.

As for other pathological issues, too, a reference center for the clinical application of DNA image cytometry might be therefore of utmost value for pathologists using that method.

Based on advanced telematic technologies, a Virtual Reference and Certification Center (VRCC) could be installed for certifying the cytometry hardware and software, the analytical procedures, and the basic interpretation of the results. It will be designed to be operated as a non‐attended service, based on quantification servers accessible via Internet round the clock. The VRCC will supply appropriate standardization and normalization materials and run a GroupWare platform for consensus making by experts.