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Analytical Cellular Pathology
Volume 33, Issue 5-6, Pages 229-244
http://dx.doi.org/10.3233/ACP-CLO-2010-0549

Inhibition of IGF-1R-Dependent PI3K Activation Sensitizes Colon Cancer Cells Specifically to DR5-Mediated Apoptosis But Not to rhTRAIL

Bodvael Pennarun,1,2 Jan H. Kleibeuker,2 Tjitske Oenema,1 Janet H. Stegehuis,1 Elisabeth G.E. de Vries,1 and Steven de Jong1

1Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
2Department of Gastroenterology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Copyright © 2010 Hindawi Publishing Corporation and the authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Bodvael Pennarun, Jan H. Kleibeuker, Tjitske Oenema, Janet H. Stegehuis, Elisabeth G.E. de Vries, and Steven de Jong, “Inhibition of IGF-1R-Dependent PI3K Activation Sensitizes Colon Cancer Cells Specifically to DR5-Mediated Apoptosis But Not to rhTRAIL,” Analytical Cellular Pathology, vol. 33, no. 5-6, pp. 229-244, 2010. https://doi.org/10.3233/ACP-CLO-2010-0549.