Research Article

Observer Performance in the Use of Digital and Optical Microscopy for the Interpretation of Tissue-Based Biomarkers

Table 8

Intermodality agreement (optical versus digital) in the assessment of Ki-67 with whole slides and TMA using percent correct and category-specific percent correct agreement [95% CI].

Intermodality Ki-67Percent correct

Scoring categoryWhole slides

All86.4 [76.5–94.5]
068.3 [47.3–85.3]
1+80.6 [65.1–92.5]

TMA

All86.8 [80.5–92.2]
074.3 [62.1–85.0]
1+78.1 [66.7–87.4]