Epstein-Barr Virus Association with Peptic Ulcer Disease
Table 3
Odds ratios for EBV or H. pylori infection and peptic ulcer disease.
Serology
Healthy controlsa
Peptic ulcer
Duodenal
Gastric
(%)
129 (100)
58 (100)
20 (100)
EBV IgA
Positives, (%)
22 (17.1)
18 (31)
14
Negatives, (%)
107 (82.9)
40 (69)
6 (30)
ORb (95% CI)
2.0 (0.9–4.6)
10.1 (3.0–33.7)
c
HP IgG
Positives, (%)
77 (59.7)
54 (93.1)
14 (70)
Negatives, (%)
52 (40.3)
4 (6.9)
6 (30)
OR (95% CI)
7.2 (2.8–20.8)
0.8 (0.3–2.7)
c
HPCagA+ IgG
Positives, (%)
52 (40.3)
43 (74.1)
9 (45)
Negatives, (%)
77 (59.7)
15 (25.9)
11 (55)
ORb (95% CI)
3.8 (1.8–8.0)
0.8 (0.3–2.4)
c
Significant differences: . aUsed as control group. bOR and cChi square for trend adjusted for age and sex and also adjusted by a robust logistic regression model.