Comparison of the Manual, Semiautomatic, and Automatic Selection and Leveling of Hot Spots in Whole Slide Images for Ki-67 Quantification in Meningiomas

Table 5

The results of intraobserver agreement examinations using Kendall’s tau-b analysis calculated based on pairwise analysis performed in uncategorized (top part) and categorized schemas. The results show coincidence between Ki-67 indexes based on 3 selections of fields of quantification by the same pathologist.

	P1 (1)	P1 (2)	P1 (3)
All
P1 (1)		0.85004 (0.8355 : 0.88658)	0.9032 (0.88398 : 0.91775)
P1 (2)	0.85948 (0.8329 : 0.88745)		0.88216 (0.85541 : 0.90649)
P1 (3)	0.86165 (0.83203 : 0.8961)	0.89835 (0.87965 : 0.92554)
Grade I
P1 (1)		0.69697 (0.66667 : 0.72727)	0.84848 (0.72727 : 0.87879)
P1 (2)	0.69697 (0.66667 : 0.72727)		0.78788 (0.75758 : 0.84848)
P1 (3)	0.84848 (0.72727 : 0.87879)	0.78788 (0.75758 : 0.84848)
Grade II
P1 (1)		0.73333 (0.73333 : 0.73333)	0.73333 (0.73333 : 0.73333)
P1 (2)	0.73333 (0.73333 : 0.73333)		1 (0.86667 : 1)
P1 (3)	0.73333 (0.73333 : 0.73333)	1 (0.86667 : 1)