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Figure 5: Kidney histological analysis of mice exposed to diphenyl ditelluride 10 μmol/kg for 7 days. (a) Kidney section of control group showing conserved architecture of cortex with convoluted tubules outlined for a single layer of cuboidal cells and preserved glomeruli (detail 40x). Kidney section of diphenyl ditelluride treated mice showing (b) vacuolar degeneration represented for marked epithelial cells swelling of renal tubules (detail 40x); (c) dilated distal tubules and proximal tubules in different stages of compression; loss of brush border and some tubular cells free in lumen; (d) hypertrophic tubules filled with eosinophilic homogeneous substance (cast proteinaceous) (H&E 10x). The picture is a representation of three independent experiments.