Comparison between Manual and Automated Methods for Ki-67 Immunoexpression Quantification in Ameloblastomas

Table 4

The cell counting methods used to determine the labeling index. Pearson’s correlation coefficient was obtained by comparing each method. The manual (manual scoring and DM scoring) and advanced ImmunoRatio methods (IRA scoring and IRpA scoring) had nearly perfect positive Pearson’s correlation coefficients, whereas the basic ImmunoRatio methods (IRB scoring and IRpB scoring) had moderate positive correlation coefficients when compared with the advanced ImmunoRatio method. Italic text indicates moderate to strong Pearson’s correlation and bold text indicates a significance level of .

Technique versus	Manual scoring	DM scoring	IRA scoring	IRpA scoring	IRB scoring	IRpB scoring
Manual scoring	N/A	r = 1.000
DM scoring	r = 1.000	N/A
IRA scoring			N/A	r = 1.000	r = 0.602	r = 0.686
IRpA scoring			r = 1.000	N/A	r = 0.601	r = 0.685
IRB scoring			r = 0.602	r = 0.601	N/A	r = 0.775
IRpB scoring			r = 0.686	r = 0.685	r = 0.775	N/A