Cofilin immunohistochemical expression in human laryngeal carcinoma. (a) Negative cofilin expression in the adjacent nonneoplastic epithelium. (b) A case of laryngeal carcinoma with low cofilin expression. Representative cases of laryngeal carcinomas with high cytoplasmic (c), nuclear (d), or cytoplasmic and nuclear cofilin expression (e). (f) A case of laryngeal carcinoma with cofilin rods. Bar corresponds to 50 μm (×400).