Expression of parvins by immunohistochemistry in human laryngeal carcinoma. (a, b) Negative expression in the adjacent nonneoplastic epithelium. (c, d) Representative cases of laryngeal carcinomas with low expression of parvins. (e, f) Representative cases of laryngeal carcinomas with high expression of α-parvin (e, cytoplasmic) and β-parvin (f, cytoplasmic and nuclear). Bar corresponds to 50 μm (×400).