High PINCH1 Expression in Human Laryngeal Carcinoma Associates with Poor Prognosis

Table 4

Univariate Cox regression analysis for overall and disease-free survival.

	Univariate analysis
	Overall survival			Disease-free survival
	HR	95% CI	value	HR	95% CI	value
Age	1.013	0.986–1.040	0.361	1.009	0.980–1.039	0.536
Location			0.999			0.756
Supraglottis/glottis	1.007	0.549–1.848	0.981	1.282	0.669–2.459	0.454
Subglottis/glottis	0.000	0.000	0.979	0.000	0.000	0.981
Grade			<0.001			0.001
Grade II/grade I	1.094	0.476–2.513	0.832	1.039	0.421–2.563	0.934
Grade III/grade I	5.076	1.855–13.893	0.002	5.018	1.679–14.997	0.004
N; (N0/N1–3)	3.157	1.707–5.839	<0.001	3.455	1.772–6.734	<0.001
Stage; (I-II/III-IV)	4.753	0.654–34.552	0.124	3.953	0.541–28.895	0.176
Cofilin cytoplasmic; Low/high	0.882	0.487–1.597	0.678	0.940	0.492–1.794	0.850
Cofilin nuclear; Low/high	0.646	0.319–1.310	0.226	0.794	0.384–1.646	0.536
N-WASP; Low/high	0.821	0.452–1.492	0.518	0.730	0.382–1.394	0.340
PARVA; Low/high	0.672	0.351–1.288	0.231	0.908	0.414–1.990	0.810
PARVB; Low/high	0.958	0.522–1.758	0.889	0.874	0.453–1684	0.687
PINCH1 cytoplasmic; Low/high	2.856	1.487–5.485	0.002	1.855	0.949–3.625	0.071
PINCH1 nuclear; Low/high	3.184	1.435–7.064	0.004	2.775	1.102–6.991	0.030

HR: hazard ratio; CI: confidence interval. Significant values appear in bold.