Metformin Treatment Inhibits Motility and Invasion of Glioblastoma Cancer Cells
Metformin treatment decreases cellular invasion in SF268 and U87 cells. Representative images showing invasive cells at the bottom side of the membrane for SF268 cells in (a) and U87 cells in (c). The cells were stained with crystal violet as per the manufacturer’s recommendations (b) and (d) show quantitation of stained SF268 and U87 cells, respectively, by colorimetric measurement using ELISA (560 nm). Data is measured in arbitrary units and normalized to the control. Data are the mean ± SEM from 3 independent experiments. indicates that the values are significant with .